Three Holroyd blackspots where 36 crashes were reported over a five-year period will be targeted with safety measures.
About $360,000 will be spent at Merrylands West and Westmead and Station Street in Wentworthville.
Roundabouts will be constructed and additional signs, line markings and pedestrian islands implemented at Merrylands West and Westmead as part of the Roads and Maritime Services' blackspot program.
Turning signals for the north and south approach to Station Street in Wentworthville will be modified.
The three sites accumulated 36 crashes between July 2006 to June 2011, with one out of seven incidents involving a pedestrian.
Holroyd mayor Nasr Kafrouni said the council would continue to maintain infrastructure.
"With speed and fatigue often factors for crashes, it is safety mechanisms like roundabouts, signs and islands that can really save lives," Cr Kafrouni said.
Design considerations were developed to cater for the needs of pedestrians with islands at Merrylands West and ramps for Westmead.